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Oncology
Phase II
Antibody-Drug Conjugate Bystander Killing
Perspectivum
628,
903-911 (2024)
·
10.1038/s41586-024-07089-9
·
NCT05168891
·
3:35
Step-by-step animation of ADC binding at HER2 antigen, lysosomal linker cleavage, payload release, and membrane-permeable toxin diffusion to antigen-negative neighbouring cells.
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