PD-1/PD-L1 Checkpoint Blockade in Non-Small Cell Lung Cancer
Visualisation of tumour-infiltrating lymphocyte reinvigoration following pembrolizumab administration, including TCR signalling cascade and apoptotic target engagement.
Visualisation of tumour-infiltrating lymphocyte reinvigoration following pembrolizumab administration, including TCR signalling cascade and apoptotic target engagement.
Step-by-step animation of ADC binding at HER2 antigen, lysosomal linker cleavage, payload release, and membrane-permeable toxin diffusion to antigen-negative neighbouring cells.
Blinatumomab-mediated formation of a cytolytic immune synapse between CD3+ T cells and CD19+ B-cell lymphoma targets, with perforin and granzyme B secretion dynamics.