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Oncology Phase II

Bi-specific T-cell Engager Synapse Formation

Perspectivum 629, 622-630 (2024) · 10.1038/s41586-024-07145-6 · NCT04546126 · 3:15

Blinatumomab-mediated formation of a cytolytic immune synapse between CD3+ T cells and CD19+ B-cell lymphoma targets, with perforin and granzyme B secretion dynamics.