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Neurology Phase II Featured

Tau Propagation in Alzheimer’s Disease

Perspectivum 627, 760-769 (2024) · 10.1038/s41586-024-07063-7 · NCT05026866 · 6:00

Trans-synaptic spread of misfolded tau seeds across hippocampal circuits, depicting uptake mechanisms, templated misfolding, and Braak stage progression.