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Pharmacology
Preclinical
mRNA Lipid Nanoparticle Endosomal Escape
Perspectivum
630,
577-585 (2024)
·
10.1038/s41586-024-07251-5
·
NCT05434832
·
2:58
Molecular dynamics-informed animation of ionisable lipid nanoparticle uptake, late endosome acidification, membrane fusion, and cytoplasmic mRNA release.
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